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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0ae1cf38db020cb3d8a1a613e21c13f7750f02414284196126a1f0722c0acd3' 
  AND token = 'pubxUw85xg29BaOc7yYNF3v0HMCEmyp1S1n2zPaYD1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}