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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b392dca8a5682b33d728015fe891fb9fe7110ba829e1306e36ffa0b98e848f2' 
  AND token = 'hCva34MxASTjFqTo0zTWSS87fy3wC946YakjM0bTMd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}