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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901fd7c8f71bb81bacb5974816a60d61be784b0aab02427d9bc2cc22f45c6d3d' 
  AND token = 'm2egaqCpnON2euc5Grqq04nbtkMpGRXqHLP5wqw19pI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}