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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25cd9cfaa13d5cdadf4156c38fe47568d62fe1cb16513a2caed7b4d7728b7c73' 
  AND token = '0/IUNZ8O5EduW0l/43IZdUtmc2GZq3yc2a7rtwGMuDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}