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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d80e0a6a1e43c6d299d48a0015047da3930c02518fef790781e9a373565c0a4' 
  AND token = 'ZQpVLzLpVKkXfdLFta0URNy886Byp/bSilL2TgCCEn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}