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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c01c41cfda22f9251f53bb6f0bd7b2123e02ed6a95f505b568866fc0a6d8342e' 
  AND token = 'ntpvQizeX4pN089MNLZhaIZxpLv+Qw2bJ0ftwje8DHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}