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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce2c5b2b1c28bb1994d8aba28410d158f8bae17aaa6b6018a768954403da17ee' 
  AND token = 'z/w0Yr1aUanlAVCah/V6S2Bs3lSAqHf8O/uGVsc9QQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}