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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39bf2c0c9c002d14257f02bb4b412fee2aaa2f7a6149da9c8f1873d12d18bd0' 
  AND token = 'bclJOH8uqTSpIYeJaIyVeU2wdqLV0sd6NxtzAAGgoQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}