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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f721c9663a7ab6ec1963a8aa09f757e94eb6e1a81b0b2cabc5d141ef2651863c' 
  AND token = 'QQ74brWjK7kqSq4PjPAFQAevWpnr+nssfRS5NLNVBWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}