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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de9b03bb350f878c91413abf1b8797af97d463da28969b882131e6ce3bcb5f9' 
  AND token = '1UDNxUvkJVt7HTVQhHdm379CbGstn7gPaYZvIV02Bnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}