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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8236a5ab97cf2feb365182b3029f2f69950d5865db3ae02b51815445375301' 
  AND token = 'EXZ7Ak6d6OeS87IoAaYRmn0bkQhsc+J8MQcO6+Fh52o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}