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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f05b4eb708aec604b73a8eede55c90bc6840cbafa2d7a27837ddb08a0df7783' 
  AND token = 'Rgz8q9MR/8d8ehlGGYjLRdwi3V7mQ4AJriMFgZPOzHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}