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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7f40415acb4b2f3a1e7f502dd5d5446ce19d397b8580a01b0dc124cc54a171f' 
  AND token = 'kLaK/V/L62JS+khTnTzOmq9i2X3tHUx7dDGQPSd99CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}