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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8918b3f69a3f56b9b52ae26c6584e2ebf2ce246c27465e9647e56944a8b143e' 
  AND token = 'R8nv4aWD/xfGtCRuUEA6sbTCzCkGsB2i/h+zPOEMHAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}