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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fe7266e4594ee62462e3fe892e29d3ad4b4e01c7e0df0f6212b74b03582df17' 
  AND token = 'skrcENHq3dtLw7o8NdapZmtTFC5O3aIUuz/ecHcJOUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}