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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '094c3653a6141950a3d4d3be3efd438e81c9170000e7dda1e6a6d7d7e0437335' 
  AND token = 'nehtFgGwJC1g2wE9RSXPNGum0YICMHePwP/DRTyFEDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}