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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5fe8812a3b1fd18d38225fc6d756819c7b24be23facc0af87605f3cb5a55416' 
  AND token = 'ENRzZGbmY8v3ekW1BRZuBnF7pv54EeR8k7gVnsNs/EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}