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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af84a5abd59d7da8204a57d7fe095747c0a1c7b9fc4b9b3246d276d3f48e994f' 
  AND token = 'B5iRXqTKCxub+ZgW1Qebfl+sufiGy6EeZw2jxq0pcjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}