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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f3ced00be497f3c81ecfed70e731eddf80c0197d2ae69e8ac82778783886ec' 
  AND token = '4JXaonO+dHpXjkcAVg2T4ORNTZfhFnuVzkRD9rNOBhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}