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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca83a59d2664132d4f6736b243be51e3e250a3eae4b206672f5eea0c9beca36' 
  AND token = 'OOe+Hq0kY+6ak4O03eYoWnjJ+BVGFVfcaUDM3GnxJrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}