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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e44981f44328b5edb7ddc902ecbd7d7a30eb9b960eb152c47491fc6b9e0b2d7' 
  AND token = 'Gq/xacDxaBASt3HbzO1fe0G/hPWbyWQlzpGM87iWqOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}