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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25e8b26f446e0349b2d751d681bbe5552e3cd8113db6207711be51cc4e0c2a3' 
  AND token = 'E1Qce/2Z+p1K759E1yBE2yt4/J1QSBNBm1t0U7D0zNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}