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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da5223d741776604307210058e8dd5cee9a1aa8db1b319f797c3bc500ffcd76b' 
  AND token = 'mD6p0AFO8swZb88gFdwPpXVjwdwu9VmEN29thU5CkI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}