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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f47f1eefc3e50fa86c5d509f4f6d2b830f1e4f8448510132963afe2f8bc5415' 
  AND token = 'OHhHiJc2ZeoOeRCHku/Hwahq6KEnD3gAbkjq4npvVCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}