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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db8ecb3f0a90d4185a7dab34a3a3ba012c2ddf1f31498b874c97caa677d469d' 
  AND token = 'Eh2mr/VqOeDnuK0aXMn1FEBtsq6VVqxJOVvbb+eXECY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}