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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57fb1421d976a54ddac2ed8b3d7bfbe000ea8ec38af53c922a73c81219a4f144' 
  AND token = 'LKS7r+Pw4w0Z+dq56Eft9vG+Dlki2A18ybPjadFo2uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}