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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f20bededafb850bb7b2f57d0e4196d5869dc7563ea5624cf30c3b65eb44664' 
  AND token = 'Zv6X425W0c5fzpBYoCvae7gQYHTvgl64TFvBMDBsBkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}