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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4483d71a7368a3b46a9c8e01805092b0bf5e0ed4aa67e98b7fb910095d03e22a' 
  AND token = 'T/CHvTBgjWpGkuTCFW1XZOuF1sZ0MPCH2ixjHM6fcGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}