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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e25b709bd3b08543afc3268896c268293756e6bfc9b48704d63fefe5a65497' 
  AND token = 'jKdDALsA/6Zb8G/MDKwfEmGUUn/KVADOjKA5qmN2MqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}