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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f586f992ca830a0d6ff56e871a83284f32b042224d8c26f0f1444f36f25a1fa' 
  AND token = 'uXal46OAguKBdOTUtEqbBW5NK2/UUnNb+0bVC9kXE/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}