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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75fd7ed68f9a7817713a1efef95bda1126b2593c279e3d77a1e05f1380a4452d' 
  AND token = 'w/aXhAhUpv8sQKvr16+dUXktWURTyKEmCb0dc9tJBtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}