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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '245ed3ccb3a64a492727efd6612eac9af537a5b4e161547fb62f4291ac40dab5' 
  AND token = 'dprq+Xgxe19qrgBYLZMCFAx/tIO2w269Uk+4g1Tniv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}