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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb6fa95969d389a2f9d3cd0ef91baf206620743e4d30871453a5ab14ac5f45db' 
  AND token = 'cqDIPG06LM2mxTngEk0zI/UequD1DBs792A8MkHhnjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}