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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '152311fb78a2089105194a9aae0e8813a1d1bbb82027ca011aa0a5ff83f1174e' 
  AND token = 'deqRSNFWdE3g4gs/O8Qdjlq6UT8FBfRKp09JdRcSLVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}