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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8249e3abd9c68f74c8da43422c955390baf9f721f1fb45bbb45b32f1b16aabca' 
  AND token = 'D+1zcUjFk6l/4rBSIDyyGY1uBi0p+I2Aycbz0TUR32c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}