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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df359bbeacd8c4f6cffd404a9b54b8ac31fc3eeca9c7e88933eafed37cf0489' 
  AND token = 'uq3Ur3wusKhP9jLQkQnIxe19Xp/eJl4yqsu4Rr2iGSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}