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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f9a280ce173ad10a16a604fe86d02f849abb214a0d221ff0424d4e4401ed59' 
  AND token = 'TMyvffV83sZdm8sGzjVhLKf4PVhwysk24iWYOUKAeIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}