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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efde6b52cab7b9aa75d137fbe98fab5fb69b12c61501c20abedf4e7bbb503f11' 
  AND token = 'qVUMKuVCK7mGIvH1yS984+SflvpsAJrxkl0Ha7fVERk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}