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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8376f0013379bfbd826c62c0e4148d49f380b1737e456711224b7725328fe3a9' 
  AND token = '5mlU1RD7Bm13uscPfAHx9TpuQ29lUYRpHb1OFUpXhEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}