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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc58b84f2d0cb43d1095e1780d113ce5c5c4454b1ce7a0e67583ae0523b8116' 
  AND token = 'RpiGAY3/hmvxgkpWS5xhg8Se2Lj0ihex9L0blU0wdrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}