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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02282592b6f1c7fc67b2b1a2b8ab280ad342b878c7030efc9bcc4ff5798907f9' 
  AND token = '6d3OH+t43+K1nMSzazrcPM2tZkpkjGb+xfH0dTD5mh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}