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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e3333e9d1ca4fc9dc91b335523a8e389dd1ac2298cb7bdc91693cdce590b69' 
  AND token = 'eZkaYUEbbi4n0sfSx0Tm7dXZT+uYxSSJDqmfWuBQ6Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00097

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}