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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98490f3db79d2a7d3e2f7bc8bc73fe07b761b35c3d9e115731df5a7eaaae32a7' 
  AND token = 'EsFy6ulbwuzpSVNXL1j3CgZQFcqFJD910xCFp+sy1Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}