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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e59f700ecded7e8914b3a6c4e44563cce4e0a504e4560668e1321d0f1da619' 
  AND token = '52i0gJ4Hgume9Yx7gm+yf04Ld9uRG/5vQeZwkojTHcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}