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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d0668ca9b447f4fafb04ee7e85965570efdeff79b96d6f0d7e800feca31cf5f' 
  AND token = 'EHqBQ6I34kWrVKTeYPO9tD51F1n/enAnHmft4KkZSdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}