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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab18383ffd8ea467fe7f70cfc65548a26bc7924dec237196c95197aa6467b243' 
  AND token = 'pLsu4sExSnFa1+7vmE/lkQ1xEn2suFQZe866Szz2UvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}