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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83d81086df8c240d5e6b803a6ca70248457d9faa5d54615906df64b260a58204' 
  AND token = 'U/uTUT6v7K73sbCAyPMch1lqpb+tsdKHXE1u7rh808I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}