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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f570534629ee5871a006e52d17499d92083c9c3966d3152c89c32595bf9cc5' 
  AND token = 'TYQX2pLMgsEXeLF7lQiBW/eCIcNgEKM04lXq82P1VLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}