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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c893b9c853fc9142dbc8f4430191a1b10b40bc861cd22d12976c03d48ec24d7' 
  AND token = 'IAqrIID4aKFUMAIbWMXn5cvbmIfEg74pykDSKTCpssI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}