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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3fdb59eb36971608e32551aaca8c565452fcfa0cf71b6debf9fb2669bf9b06' 
  AND token = 'A9p8JJYBnPmmK5JalSSvSkiAvmGh6PC0rupRdSV/aTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}